LuciPlex is a comprehensive brain health formula comprised of a proprietary blend of natural ingredients formulated and clinically validated to improve memory, focus and cognition.  In clinical trials, components of LuciPlex were shown to slow the onset of brain atrophy, dementia as well as other neurodegenerative disorders.

The patented ingredients in LuciPlex were designed to work synergistically to reduce the risk of “all-cause-mortality” as well as provide a comprehensive nutritional formula necessary to optimize overall neurological health. As with all of USH Integratives, what is left out is as important as what is included. Heavy metals such as copper, manganese, aluminum have been intentionally eliminated from LuciPlex because multiple studies confirm they may negatively affect brain function and overall health.

LuciPlex™ Supplement Facts – Download

Key Ingredients & Benefits

LuciPlex Ingredients

LuciPlex contains three patented ingredients that cannot be found together in any product. This clinically validated blend of patented and supporting ingredients have been specifically selected by our board certified pharmacologists and drug development scientists because of their superior quality, purity and absorption properties.

BCM-95 is the only 100% pure turmeric extract and most bioavailable version available today that is manufactured without the use of harmful chemicals. To receive the health benefits associated with turmeric, concentration and absorption are critical for success. BCM-95 works by balancing the body’s inflammation response and the synthesis of enzymes. This helps stimulate the immune system, which may help in the fight against the onset of degenerative diseases like Alzheimer’s Disease.

In clinical studies, turmeric (curcuminoids) has been shown to:

  • Increase neural stem cell generation
  • Reduce inflammation of nerve cells in patients with Alzheimer’s Disease (AD)
  • Reduce beta-amyloid plaques linked to AD
  • Improve mood in patients with symptoms of depression

LuciPlex contains Sharp-PS GOLD because it is a unique, highly bioavailable form of Phosphatidylserine (PS). It is readily absorbed and highly potent. It has been shown to elevate docosahexaenoic acid (DHA) to the brain. Unlike pure vegetable source PS, the molecular structure of Sharp-PS GOLD resembles the structure of PS in the brain, resulting in improved absorption and achieving its full benefits. Phosphatidylserine is important in the transport of DHA to the brain, an essential fatty acid that works everyday to help tissues in the brain function at their highest levels.

In clinical studies, phosphatidylserine has been shown to:

  • Positively influence levels of neurotransmitters
  • Enhance areas of the brain that process visual information
  • Improve overall behavior and mental function
  • Improve verbal recall


SelenoExcell was chosen because it is highly bioavailable and has been certified to contain 100% organically bound selenium. This ensures consistent high quality and elevated absorption rates with every use. SelenoExcell, proven in human clinical studies to raise healthy anti-oxidant levels, helps to reduce the formation of free radicals and fights brain cell damage on a daily basis. It helps you take steps to preserve cognitive health over time.

In clinical studies, selenium deficiencies have been linked to:

  • Lower cognitive function
  • Increases in protein oxidation
  • Increases in the rate of “all-cause mortality” in the elderly


LuciPlex includes a proprietary blend of Folic Acid, Vitamin B6 and Vitamin B12. The volume and ratio of the actives are based on those used in the “VITACOG” study. This blend in the study indicated that the combination could substantially reduce brain atrophy in the elderly.

In clinical studies, these ingredients have been shown to:

  • Reduce brain shrinkage caused by aging including regions of the brain affected by Alzheimer’s Disease
  • Slow the onset of cognitive decline
  • Reduce the rate of brain atrophy

Other ingredients include: Vitamins A, C, D3, E and K, Thiamine, Riboflavin, Niacin, Biotin, Pantothenic Acid, Iron, Iodine, Zinc, Chromium, Molybdenum, Boron, Nickel, Silicon, Tin and Vanadium. The other ingredients found in LuciPlex were specifically chosen for their ability to provide daily nutritional value to the brain and rest of the body. This helps to increase the effect LuciPlex has on improving overall brain health and quality of life.

Copper – Though an essential nutrient in our diets, the average person takes in enough copper through the daily foods and liquids we ingest. Too much copper intake has been linked to liver and kidney damage, and has also been shown to increase growth of certain types of cancer.

Manganese – Long-term ingestion of supplements that include manganese has been linked to many forms of neurological and behavior disorders. Though the data is not absolute, we purposely chose to not include manganese in our formulation

Excess Iron – The reason LuciPlex does not include 100% the daily nutritional value of iron suggested by the FDA is that some data shows iron supplements may increase “all-cause mortality”. Most of us consume plenty of iron with the foods we eat – including more iron in our formulation could lead to excess iron levels.

Aluminum – Various studies have shown that multiple forms of aluminum have been linked to cognitive decline and neurodegenerative disease states.

Green Tea Extract – Recently, clinical data has shown that green tea extract absorption is very low, making benefits associated with it hard to achieve. Also, green tea extract has been linked to some cases of liver failure.


LuciPlex is a new, multi-faceted, naturally derived “Integrative” product designed to maintain and restore neurological health. It was developed by accomplished medical scientists and contains a unique blend of proprietary ingredients formulated to help improve memory and cognition, slow natural brain atrophy, and to restore overall neurological health.
No. There are enormous variations in quality, consistency and stability. Some supplements may do more harm than good. Independent lab evaluations of supplements indicate half would be considered “clinically adulterated” if they were held to higher production standards similar to those of prescription medications.Because they are not highly regulated they are subject to fraud, misrepresentation and benefit exaggeration. Anyone who is depending on a supplement to generate a true health benefit needs to select a product with the aid of a health care professional. Their impact should be monitored for effect. USH “Integrative” products are made to prescription standards and are available only via physician recommendation. They are absorbed and in forms useful to the body and brain.
LuciPlex was created to be used under the direction of an experienced healthcare professional. Its proprietary blend of patented active ingredients have been clinically validated in multiple studies and produce specific patient benefits. The developers of LuciPlex spent years perfecting the quantity and quality of each ingredient. These items have been blended to work synergistically and not counteract the impact of the other ingredients. The result is a product that yields optimal absorption and in the amounts necessary to improve neurological and cognitive function.

The proprietary blend of patented ingredients in LuciPlex were specifically formulated to work in harmony to:

  • Improve and/or maintain overall brain health. LuciPlex’s active ingredients have been clinically validated to: Improve memory by regulating your body’s own natural production of DHA and EPA. (DHA and EPA are essential nutrients necessary to maintain healthy brain function. Both may help repair neurological trauma and facilitate memory retention. They also play a role in forming neural transmitters, which are also important to healthy brain function.)
  • Reduce inflammation and oxidation.
  • Provide essential nutrients to facilitate healthy brain function.
  • Mitigate brain cell damage and reduce brain trauma caused by toxins and brain shrinkage due to the aging process.
Follow your physician’s recommendations. Most patients take 2 tablets a day with food. USH does not recommend taking more than 2 tablets in a 24-hour period unless otherwise directed by a physician.


LuciPlex Clinicals

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Cenacchi, T., et al. “Cognitive Decline in the Elderly: a Double-Blind, Placebo-Controlled Multicenter Study on Efficacy of Phosphatidylserine Administration.”Aging Clinical and Experimental Research 5.2 (1993): 123-133. Web. 20 May 2014.

Crook, T.H., PhD, et al. “Effects of Phosphatidylserine in Age-Associated MemoryImpairment.” Neurology 41 (1991): 644-649. Print. July 2014.

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Young, Genevieve and Julie Conquer. “Omega-3 Fatty Acids and Neuropsychiatric Disorders.” Reproduction Nutrition Development 45 (2005): 1-28. Web. July 2014.

Antony, B., et al. “A Pilot Cross-Over Study to Evalutae Human Oral Bioavailability ofBCM-95®CG (Biocurcumax™), A Novel Bioenhanced Preparation of Curcumin.”Indian Journal of Pharmaceutical Sciences 70.4 (2008): 445-449. Web. July 2014.

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Chin, Dawn, et al. “Neuroprotective Properties of Curcumin – Merits andLimitations.” Current Medicinal Chemistry 20.32 (2013): 3955-3985. Web. July 2014.

Sanmukhani, Jayesh, Ashish Anovadiya and Chandrabhanu B. Tripathi. “Evaluationof Antidepressant Like Activity of Curcumin and Its Combination with Fluoxetine and Imipramine: an Acute and Chronic Study.” Acta Poloniae Pharmaceutica – DrugResearch 68.5 (2011): 769-775. Print. July 2014.

Sanmukhani, Jayesh, et al. “Efficacy and Safety of Curcumin in Major DepressiveDisorder: A Randomized Controlled Trial.” Phytotherapy Research (2013). Web. July 2014.

Akbaraly, N. Tasnime, et al. “Plasma Selenium Over Time and Cognitive Decline inthe Elderly: Results of the EVA Study.” Epidemiology 18.1 (2007): 52-58. Print. July2014.

Cheng, Y., et al. “Abstract of [Study on Selenium Exposure Level Related to CognitiveFunction in Rural Elderly People].” Wei Sheng Yan Jiu = Journal of Hygiene Research39.4 (2010): 483-485. Web. July 2014 [Full Journal in Chinese].

Daniells, Stephen. Lifelong Selenium Intake May Slow Age-Related Cognitive Decline.Commentary on “Selenium Level and Cognitive Function in Rural Elderly Chinese”.William Reed Business Media. 13 February 2007. Web. July 2014.—.

Selenium Supplements Could Slow Age-Related Cognitive Decline. Commentaryon “Plasma Selenium Over Time and Cognitive Decline in the Elderly. William Reed Business Media. 2 February 2007. Web. July 2014.

Gao, Sujuan, et al. “Selenium Level and Cognitive Function in Rural Elderly Chinese.”American Journal of Epidemiology 165 (2007): 955-965. Web. July 2014.—. “Selenium Level is Associated with apoE E4 in Rural Elderly Chinese.” Public Health Nutrition 12.12 (2009): 2371-2376. Web. July 2014.

Ishrat, Tauheed, et al. “Selenium Prevents Cognitive Decline and Oxidative Damagein Rat Model of Streptozotocin-Induced Experimental Dementia of Alzheimer’sType.” Brain Research 1281.24 (2009): 117-127. Web. 20 May 2014.

Annweiler, Cédric, et al. “Higher Vitamin D Dietary Intake is Associated with LowerRisk of Alzheimer’s Disease: a 7-Year Follow-up.” J Gerontol A Biol Sci Med Sci 67.11(2012): 1205-1211. Web. July 2014.

de Jager, Celeste A., et al. “Cognitive and Clinical Outcomes of Homocysteine-Lowering B-Vitamin Tratment in Mild Cognitive Impairment: a RandomizedControlled Trial.” International Journal of Geriatric Psychiatry 27.6 (2012): 592-600.Web. July 2014.

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